Download e-book for iPad: Brain development by Lakshmi Bangalore

By Lakshmi Bangalore

ISBN-10: 0791089541

ISBN-13: 9780791089545

"Brain improvement" introduces uncomplicated mind anatomy and mind improvement to school scholars. It discusses the molecular foundation of critical anxious approach specification, ranging from neural induction and trend formation to neural migration, axon counsel, and synapse formation. It additionally discusses the function that have and plasticity play in shaping the constitution and serve as of the constructing mind.

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Extra resources for Brain development

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When the population of oligodendrocyte precursors expands to sufficient numbers—usually at the time of birth—they migrate through the developing central nervous system in search of neurons destined to be myelinated. As they make contact with axons of their target neurons, they begin to turn into mature oligodendrocytes. They stop dividing and start producing myelin-specific proteins and fats. They extend many branch-like structures in preparation for wrapping the axons. A single oligodendrocyte can extend as many as 50 to 60 branch-like structures that end in sheets of myelin membrane and is able to myelinate a variety of axons in its area.

Target cells release trophic factors that are necessary for the continued survival of the neurons. Neurons that are able to get enough trophic factors survive, while the others die. ■ Learn more about the contents of this chapter Search the Internet for Santiago Ramón y Cajal, Rita Levi-Montalcini, and nerve growth factor. 5 Network Connectivity: Formation and Strengthening of Synapses No matter how well the birth, migration, and differentia- tion of neurons are choreographed, the human brain cannot function unless proper connections are made between neurons and their target cells.

They rarely survive beyond a few years of life. Similarly, in Kallman syndrome, neurons that produce sex hormones and neurons that sense odors fail to migrate to their proper locations. This results in underdeveloped genitalia, sterile gonads, and complete or partial loss of the ability to smell. Still, precisely how errors in neuronal migration cause diseases remains unclear. Environmental factors can also prevent migrating neurons from reaching their proper destination. These include exposure of the developing fetus to alcohol, cocaine, viral and bacterial infections, or radiation.

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Brain development by Lakshmi Bangalore

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